FAQ
Your questions answered. Unless they aren't...in which case, please contact support!
Please note, in addition to the supplements provided, for best results, you'll need proper hydration-- with water and electrolytes which are not included -- and a proper night's sleep.
When should I take them?
We recommend taking them with your 2nd or 3rd drink. The founders like to take them at midnight on a normal night out.
What's in it? B-complex, L-Cysteine (a pre-cursor to NAC), Milk Thistle, and Alpha Lipoic Acid.
What does the B-complex do?
1. Alcohol’s Impact on B Vitamin Levels:
Alcohol consumption can interfere with the absorption and utilization of B vitamins, leading to their depletion. This reduction may contribute to common hangover symptoms such as fatigue, weakness, and mood disturbances. Replenishing these vitamins might help mitigate some of these effects.
2. Metabolic Support:
Certain B vitamins are integral to metabolizing alcohol. For instance, thiamine (B1) and pyridoxine (B6) assist enzymes that break down alcohol in the liver. Ensuring adequate levels of these vitamins may support more efficient alcohol metabolism, potentially reducing the severity of hangover symptoms.
What about L-Cysteine?
1. Neutralizing Acetaldehyde: When alcohol is consumed, it’s metabolized in the liver into acetaldehyde, a toxic compound responsible for many hangover symptoms such as nausea and headaches. L-cysteine contributes to the breakdown of acetaldehyde into less harmful substances, potentially reducing these adverse effects.
2. Supporting Alcohol Metabolism: L-cysteine may enhance the activity of enzymes like alcohol dehydrogenase and aldehyde dehydrogenase, which are crucial for metabolizing alcohol and acetaldehyde. This support can lead to a more efficient detoxification process, potentially mitigating hangover severity.
3. Reducing Oxidative Stress: Alcohol consumption can increase oxidative stress, contributing to hangover symptoms and liver damage. L-cysteine has antioxidant properties that help combat oxidative stress, thereby protecting liver cells and possibly alleviating hangover-related discomfort.
And Milk Thistle?
This is to support liver health due to its antioxidant and anti-inflammatory properties. These properties might help mitigate hangover symptoms by aiding liver function and promoting the detoxification of alcohol.
What about Alpha Lipoic Acid?
1. Enhancement of Acetaldehyde Metabolism:
After alcohol consumption, the liver metabolizes ethanol into acetaldehyde, a toxic compound contributing to hangover symptoms. ALA has been shown to activate aldehyde dehydrogenase 2 (ALDH2), the enzyme responsible for converting acetaldehyde into less harmful substances. By promoting this conversion, ALA may help reduce acetaldehyde accumulation, potentially mitigating hangover severity.
2. Antioxidant Properties and Reduction of Oxidative Stress:
Alcohol metabolism increases the production of reactive oxygen species (ROS), leading to oxidative stress and cellular damage. ALA functions as a potent antioxidant, neutralizing ROS and thereby protecting cells from oxidative damage. This action may alleviate some physiological stress associated with hangovers.
3. Support for Glutathione Production:
ALA plays a role in regenerating glutathione, a critical antioxidant involved in detoxifying harmful substances, including those produced during alcohol metabolism. Enhanced glutathione levels can aid in more efficient processing and elimination of toxins, potentially reducing hangover symptoms.